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English(EN) scAnyOmics: Foundation-Model Distillation for Any-to-Any Completion of Multi-omics Virtual Cells

新的scAnyOmics框架整合多组学数据用于虚拟细胞模型

研究人员开发了scAnyOmics,一个新颖的生成框架,旨在整合和预测来自不完整单细胞多组学数据的缺失分子信息。该框架将知识从预训练的基础模型蒸馏到一个多模态学生模型中,实现了跨模态预测和重构转录组学、蛋白质组学和染色质可及性等数据。在包含690,880个细胞的大型数据集上进行评估,scAnyOmics在重构缺失模态方面表现优于基线方法,并在细胞类型注释和生物年龄估计等应用中显示出潜力。 AI

影响 通过整合不同的分子测量数据,实现了对生物数据的更全面分析。

排序理由 该集群包含一篇关于用于生物数据分析的新计算框架的学术论文。[lever_c_demoted from research: ic=1 ai=1.0]

在 arXiv cs.AI 阅读 →

AI 生成摘要 · Google Gemini · 来自 1 个来源。 我们如何撰写摘要 →

新的scAnyOmics框架整合多组学数据用于虚拟细胞模型

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该集群包含一篇关于用于生物数据分析的新计算框架的学术论文。[lever_c_demoted from research: ic=1 ai=1.0]
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报道来源 [1]

  1. arXiv cs.AI TIER_1 English(EN) · Zhaoqi Song, Ye Du, Yusuke Iwasawa, Yutaka Matsuo, Qian Niu ·

    scAnyOmics: Foundation-Model Distillation for Any-to-Any Completion of Multi-omics Virtual Cells

    arXiv:2610.41399v1 Announce Type: new Abstract: Recent advances in single-cell technologies have enabled the profiling of multiple molecular modalities, including transcriptomics, proteomics, and chromatin accessibility, providing a more comprehensive understanding of cellular st…