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Radiogenomic models predict glioblastoma immune signatures

Researchers have developed radiogenomic models capable of non-invasively predicting a specific immune cell signature in glioblastoma. These models utilize radiomic features extracted from MRI scans and transcriptomic data to identify macrophage subtype M0 immune signatures. The study, involving 176 patients across multiple datasets, demonstrated stable performance and potential for stratifying patients for immunotherapy in future clinical trials. AI

影响 This research offers a non-invasive method to predict patient immune signatures, potentially improving immunotherapy stratification for glioblastoma.

排序理由 The cluster contains an academic paper detailing a new research methodology and findings. [lever_c_demoted from research: ic=1 ai=1.0]

在 arXiv cs.LG 阅读 →

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Radiogenomic models predict glioblastoma immune signatures

报道来源 [1]

  1. arXiv cs.LG TIER_1 English(EN) · Thomas Booth ·

    Predictive Radiomics for Evaluation of Cancer Immune SignaturE in Glioblastoma: the PRECISE-GBM study

    Background: Radiogenomics allows identification of radiological biomarkers for genomic phenotypes. In glioblastoma, these biomarkers could potentially complement patient stratification strategies. We aim to develop and analytically validate radiological biomarkers that capture im…