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New framework RE-CONFIRM evaluates robustness of AI biomarkers for neurological disorders

Researchers have developed a new framework called RE-CONFIRM to evaluate the robustness of biomarkers identified by foundation models (FMs) for neurological disorders. Experiments on datasets for Autism Spectrum Disorder (ASD), Attention-deficit Hyperactivity Disorder (ADHD), and Alzheimer's Disease (AD) revealed that standard performance metrics are insufficient for assessing biomarker reliability. The study also introduced Hub-LoRA, a fine-tuning technique that improves FM performance and generates more neurobiologically accurate biomarkers. AI

影响 Introduces a new evaluation framework and fine-tuning method for AI models in neuroscience, potentially improving biomarker discovery for neurological disorders.

排序理由 Academic paper introducing a new framework and fine-tuning technique for evaluating AI models in neuroscience.

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New framework RE-CONFIRM evaluates robustness of AI biomarkers for neurological disorders

报道来源 [2]

  1. arXiv cs.LG TIER_1 English(EN) · Deepank Girish, Yi Hao Chan, Sukrit Gupta, Jing Xia, Jagath C. Rajapakse ·

    Foundation models for discovering robust biomarkers of neurological disorders from dynamic functional connectivity

    arXiv:2604.22018v1 Announce Type: cross Abstract: Several brain foundation models (FM) have recently been proposed to predict brain disorders by modelling dynamic functional connectivity (FC). While they demonstrate remarkable model performance and zero- or few-shot generalizatio…

  2. arXiv cs.AI TIER_1 English(EN) · Jagath C. Rajapakse ·

    Foundation models for discovering robust biomarkers of neurological disorders from dynamic functional connectivity

    Several brain foundation models (FM) have recently been proposed to predict brain disorders by modelling dynamic functional connectivity (FC). While they demonstrate remarkable model performance and zero- or few-shot generalization, the salient features identified as potential bi…