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English(EN) Bridging Graph and Pairwise Learning for Gene Regulatory Network Inference from scRNA-seq Data

新的scGPL框架增强了基因调控网络的推断

研究人员开发了scGPL,这是一个新颖的框架,旨在改进从单细胞RNA测序数据中推断基因调控网络(GRNs)。该方法整合了基于图和成对的学习方法,通过同时考虑全局拓扑结构和局部TF-目标基因相互作用来解决各自的局限性。实验表明,scGPL的性能显著优于现有方法,在基准数据集上的改进高达13.7%。该框架的代码可在GitHub上公开获取,以确保可复现性。 AI

影响 增强了生物数据分析能力,有望加速基因组学和系统生物学领域的发现。

排序理由 该集群描述了一篇发表在arXiv上的新研究论文,其中详细介绍了一种用于生物数据分析的新型计算框架。[lever_c_demoted from research: ic=1 ai=0.7]

在 arXiv cs.AI 阅读 →

AI 生成摘要 · Google Gemini · 来自 1 个来源。 我们如何撰写摘要 →

新的scGPL框架增强了基因调控网络的推断

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该集群描述了一篇发表在arXiv上的新研究论文,其中详细介绍了一种用于生物数据分析的新型计算框架。[lever_c_demoted from research: ic=1 ai=0.7]
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报道来源 [1]

  1. arXiv cs.AI TIER_1 English(EN) · Hang Li, Jiaxin Qi, Yan Cui, Yuhua Zheng, Jianqiang Huang ·

    从scRNA-seq数据中推断基因调控网络的图与成对学习的桥接

    arXiv:2611.13801v1 Announce Type: cross Abstract: Motivation: Gene regulatory networks (GRNs) capture the underlying interactions through which transcription factors (TFs) regulate genes. Based on gene expression data, existing GRN inference approaches generally fall into two cat…