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English(EN) This is exploratory work, and we’re not claiming to have produced an antivenom—for that, we’d have to test the binders within living cells, then in mice, among

Anthropic的Claude AI助力蝎子毒素结合剂设计，数据已发布

作者 PulseAugur 编辑部 · [5 个来源] ·

Anthropic利用其Claude AI模型协助设计靶向蝎子神经毒蛋白的蛋白质结合剂。该AI生成了超过30万个蛋白质设计，其中211个被选中进行实验室测试。在这些设计中，有17个对来自墨西哥、北非和中东蝎子的毒素表现出结合能力。Anthropic将测试过的设计和实验室数据发布给科学界，以帮助进一步研究开发潜在的抗毒剂，并承认这是一个早期的探索性步骤。 AI

影响 这项研究展示了AI在加速科学发现方面的潜力，可应用于抗毒剂开发等关键领域。

排序理由 Anthropic发布了在AI辅助下生成的针对蝎子毒素的蛋白质结合剂的研究数据和设计。

在 X — Anthropic 阅读 →

AI 生成摘要 · Google Gemini · 来自 5 个来源。 我们如何撰写摘要 →

Anthropic的Claude AI助力蝎子毒素结合剂设计，数据已发布

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Anthropic发布了在AI辅助下生成的针对蝎子毒素的蛋白质结合剂的研究数据和设计。
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报道来源 [5]

  1. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    我们将发布所有 211 个经过测试的设计和实验室数据，供科学家参考：https://t.co/zqke30UV2o

    We’re releasing all 211 of the tested designs and the lab data as a resource for scientists: https://t.co/zqke30UV2o Read the full technical report: https://t.co/ikWVcFxnyP

  2. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    这是探索性工作，我们并未声称已生产出抗蛇毒血清——为此，我们必须在活细胞中测试结合剂，然后在小鼠体内进行测试，其中

    This is exploratory work, and we’re not claiming to have produced an antivenom—for that, we’d have to test the binders within living cells, then in mice, among many other steps. But it’s an example of how Claude can concretely assist research in protein design.

  3. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    211名中的17名符合结合剂标准。它们与墨西哥、北非和中东蝎子产生的有毒物质结合（但不是由s产生的）

    17 of the 211 met the criteria for a binder. They bound to dangerous toxins produced by scorpions from Mexico, North Africa, and the Middle East (but not by a species from Brazil). https://t.co/GEizpvhlQX

  4. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    我们与@citrini合作，让Claude设计能结合五种蝎子毒素的蛋白质（覆盖毒素附着细胞的部分）。

    Working with @citrini, we asked Claude to design proteins that bind to five scorpion toxins (covering the part of the toxin that latches onto cells). Over the next 64 hours, Claude generated over 300,000 designs; we sent 211 to @adaptyvbio and @TwistBioscience for lab testing.

  5. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    我们科学博客新文章：设计靶向蝎子神经毒素的蛋白质结合剂。

    New on our Science Blog: designing protein binders against scorpion neurotoxins. Scorpions sting about 1.2m people every year, and antivenoms are often costly or in short supply. Claude has made an early step toward finding new treatments. https://t.co/l6LgdEqM7I

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