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English(EN) RIBOSPAN: A Long-Context RNA Foundation Model for Versatile RNA Modeling

RIBOSPAN模型推动长上下文RNA分析和设计

研究人员推出RIBOSPAN,这是一个拥有16.1亿参数的双向基础模型,专为长上下文RNA建模而设计。该模型原生支持长达10,240个核苷酸的上下文长度,能够对完整的RNA转录本进行高分辨率分析。RIBOSPAN在学习RNA表示方面展现了最先进的性能,并在预测生物学特性和建模突变适应性方面取得了顶级结果,尤其是在较长的RNA序列上。此外,基于RIBOSPAN骨干的扩散框架促进了mRNA的生成和重新设计,包括蛋白质保留的密码子优化。 AI

影响 为长上下文RNA建模奠定了新基础,有望加速生物学发现和mRNA设计。

排序理由 该集群描述了一篇详细介绍用于RNA分析的新型基础模型的研究论文。[lever_c_demoted from research: ic=1 ai=1.0]

在 arXiv cs.LG 阅读 →

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RIBOSPAN模型推动长上下文RNA分析和设计

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该集群描述了一篇详细介绍用于RNA分析的新型基础模型的研究论文。[lever_c_demoted from research: ic=1 ai=1.0]
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报道来源 [1]

  1. arXiv cs.LG TIER_1 English(EN) · Ziyuan Wang, Bohao Tang, Fei Zhang, Shuo Han, Pengfei Liu ·

    RIBOSPAN:用于多功能 RNA 建模的长上下文 RNA 基础模型

    arXiv:2608.22849v2 Announce Type: replace Abstract: Full-length RNAs, particularly messenger RNAs, often exceed the context lengths used to pretrain existing RNA foundation models, limiting complete-transcript modeling at single-nucleotide resolution. We present RIBOSPAN, a 1.61-…