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English(EN) Fitting Large Nonlinear Mixed Effects Models Using Variational Expectation Maximization

VEM算法可扩展至拟合拥有超过15,000个参数的大型非线性混合效应模型

研究人员探索了变分期望最大化(VEM)算法作为一种可扩展的方法,用于拟合非线性混合效应(NLME)模型,尤其是在处理大量参数时。该方法借鉴了概率图模型和变分自编码器的思想,为传统计算成本高昂的方法提供了一种高效的替代方案。该论文详细介绍了VEM在NLME中的应用,并使用Pumas统计软件展示了其处理拥有超过15,000个总体参数的模型的能力。 AI

影响 提出了一种可扩展的统计方法,有望提高复杂模型拟合在各个科学领域的效率。

排序理由 这是一篇研究论文,详细介绍了一种拟合统计模型的新方法。

在 arXiv cs.LG 阅读 →

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VEM算法可扩展至拟合拥有超过15,000个参数的大型非线性混合效应模型

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报道来源 [2]

  1. arXiv cs.LG TIER_1 English(EN) · Mohamed Tarek, Pedro Afonso ·

    使用变分期望最大化拟合大型非线性混合效应模型

    arXiv:2604.26160v1 Announce Type: cross Abstract: Nonlinear Mixed Effects models (NLME) models are widely used in pharmacometrics and related fields to analyze hierarchical and longitudinal data. However, as the number of parameters and random effects increases, traditional metho…

  2. Hugging Face Daily Papers TIER_1 English(EN) ·

    使用变分期望最大化拟合大型非线性混合效应模型

    Nonlinear Mixed Effects models (NLME) models are widely used in pharmacometrics and related fields to analyze hierarchical and longitudinal data. However, as the number of parameters and random effects increases, traditional methods for maximizing the marginal likelihood become c…