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English(EN) Donated livers can be made biologically younger

通过机器灌注使捐赠的肝脏在生物学上变得更年轻

科学家们发现,放置在机器灌注系统中的捐赠肝脏在生物学上似乎变得更年轻。研究人员使用表观遗传学和基因表达的“衰老时钟”发现,即使在时间上更老的肝脏,经过灌注后,其生物年龄也比储存在冰上的肝脏低。这种效应表明灌注可以将生物衰老逆转约30%,这可能解释了为什么灌注的器官在移植后表现更好,并可能带来改进的器官利用和修复策略。 AI

排序理由 关于器官生物衰老的研究发现。[lever_c_demoted from research: ic=1 ai=0.0]

在 MIT Technology Review 阅读 →

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通过机器灌注使捐赠的肝脏在生物学上变得更年轻

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关于器官生物衰老的研究发现。[lever_c_demoted from research: ic=1 ai=0.0]
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报道来源 [1]

  1. MIT Technology Review TIER_1 English(EN) · Jessica Hamzelou ·

    捐赠的肝脏可以变得更年轻

    Once an organ is removed from a donor’s body, the clock starts ticking. Surgeons usually flush the organ with a preservative solution, bag it, and put it on ice—where it immediately starts to degrade. The team has a matter of hours to get it into a recipient’s body. There’s anoth…