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研究发现:LLM提示工程对药物毒性预测影响有限

一篇新研究论文探讨了使用大型语言模型(LLMs)进行药物毒性预测的提示工程的有效性。研究发现,LLMs固有的方差显著超过了提示优化的影响,表明提示措辞对预测准确性的影响有限。然而,与LLM生成的数值相比,该研究确实证明了在使用化学信息学代码进行特征提取时取得了实质性的性能提升。所提出的方法适用于生物信息学中各种类型的提示。 AI

影响 表明虽然LLMs在药物发现中有用,但其固有的可变性需要仔细考虑特征提取方法而非提示优化。

排序理由 研究论文发表在arXiv上,详细介绍了分析LLMs中用于药物毒性预测的提示工程的新方法。[lever_c_demoted from research: ic=1 ai=1.0]

在 arXiv cs.AI 阅读 →

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研究发现:LLM提示工程对药物毒性预测影响有限

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研究论文发表在arXiv上,详细介绍了分析LLMs中用于药物毒性预测的提示工程的新方法。[lever_c_demoted from research: ic=1 ai=1.0]
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报道来源 [1]

  1. arXiv cs.AI TIER_1 English(EN) · Mia MacGregor, Aakash Welgamage Don, Mark Bartlett ·

    药物毒性预测的提示工程分析

    arXiv:2609.03635v1 Announce Type: new Abstract: Clinical trials in the UK can cost up to {\pounds}1.3 million, with approximately 90% drug failure rate. Toxicity is a major contributing factor in drug failure. Testing is time and cost intensive. In recent years, the use of artifi…