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LLMs show promise in diagnosing dementia and depression from interviews

Researchers have explored the use of open-weights Large Language Models (LLMs) to assess dementia and depression severity from clinical interview transcripts. The study compared three LLMs—Mistral 3.1, DeepHermes, and Qwen3—using both zero-shot prediction and feature extraction for Support Vector Regression. Results indicated that LLMs are effective for predicting depression severity in a zero-shot setting, achieving a mean absolute error of 0.60. Dementia assessment, however, saw significant improvement with structured feature extraction, reducing errors by up to 35% compared to zero-shot methods. AI

IMPACT LLMs demonstrate potential for automated screening of neuropsychiatric disorders, aiding in differential diagnosis and reducing diagnostic errors.

RANK_REASON The cluster contains an academic paper detailing research findings on LLM application for medical assessment. [lever_c_demoted from research: ic=1 ai=1.0]

Read on arXiv cs.CL →

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COVERAGE [1]

  1. arXiv cs.CL TIER_1 English(EN) · Korbinian Riedhammer ·

    Reading between the Lines: Leveraging Large Language Models for Global Dementia and Depression Assessment from Clinical Interviews

    Dementia and depression are the most prevalent neuropsychiatric disorders in geriatric populations, and their overlapping symptoms pose major challenges for differential diagnosis. In this study, we investigate open-weights Large Language Models (LLMs) for predicting dementia and…