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Anthropic's Claude AI aids scorpion toxin binder design, data released

By PulseAugur Editorial · [5 sources] ·

Anthropic has utilized its Claude AI model to assist in the design of protein binders targeting scorpion neurotoxins. The AI generated over 300,000 protein designs, with 211 selected for lab testing. Of these, 17 demonstrated binding capabilities against toxins from scorpions in Mexico, North Africa, and the Middle East. Anthropic is releasing the tested designs and lab data to the scientific community to aid further research in developing potential antivenoms, acknowledging this is an early exploratory step. AI

IMPACT This research demonstrates AI's potential in accelerating scientific discovery for critical applications like antivenom development.

RANK_REASON Anthropic released research data and designs for protein binders against scorpion toxins, generated with AI assistance.

Read on X — Anthropic →

AI-generated summary · Google Gemini · from 5 sources. How we write summaries →

Anthropic's Claude AI aids scorpion toxin binder design, data released

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Anthropic released research data and designs for protein binders against scorpion toxins, generated with AI assistance.
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COVERAGE [5]

  1. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    We’re releasing all 211 of the tested designs and the lab data as a resource for scientists: https://t.co/zqke30UV2o

    We’re releasing all 211 of the tested designs and the lab data as a resource for scientists: https://t.co/zqke30UV2o Read the full technical report: https://t.co/ikWVcFxnyP

  2. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    This is exploratory work, and we’re not claiming to have produced an antivenom—for that, we’d have to test the binders within living cells, then in mice, among

    This is exploratory work, and we’re not claiming to have produced an antivenom—for that, we’d have to test the binders within living cells, then in mice, among many other steps. But it’s an example of how Claude can concretely assist research in protein design.

  3. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    17 of the 211 met the criteria for a binder. They bound to dangerous toxins produced by scorpions from Mexico, North Africa, and the Middle East (but not by a s

    17 of the 211 met the criteria for a binder. They bound to dangerous toxins produced by scorpions from Mexico, North Africa, and the Middle East (but not by a species from Brazil). https://t.co/GEizpvhlQX

  4. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    Working with @citrini, we asked Claude to design proteins that bind to five scorpion toxins (covering the part of the toxin that latches onto cells).

    Working with @citrini, we asked Claude to design proteins that bind to five scorpion toxins (covering the part of the toxin that latches onto cells). Over the next 64 hours, Claude generated over 300,000 designs; we sent 211 to @adaptyvbio and @TwistBioscience for lab testing.

  5. X — Anthropic TIER_1 English(EN) · AnthropicAI ·

    New on our Science Blog: designing protein binders against scorpion neurotoxins.

    New on our Science Blog: designing protein binders against scorpion neurotoxins. Scorpions sting about 1.2m people every year, and antivenoms are often costly or in short supply. Claude has made an early step toward finding new treatments. https://t.co/l6LgdEqM7I

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