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Chest X-ray AI models show limited real-world performance in multinational study

A new retrospective study evaluated ten Chest X-ray AI models across twelve datasets from six countries, including both public benchmarks and private institutional cohorts. The research found that while models like MAVL and MedKLIP showed the highest specificity at 95% sensitivity, their positive predictive value was low, indicating many false positives. Performance on institutional data was generally lower than on public benchmarks, suggesting that current evaluations may overstate real-world applicability. The study emphasizes the need for operating-point-aware evaluation and external validation on institutional data before deploying these AI models. AI

IMPACT Highlights the gap between AI model performance on benchmarks and real-world clinical utility, urging caution in deployment.

RANK_REASON The cluster is a research paper published on arXiv detailing a study on AI model performance. [lever_c_demoted from research: ic=1 ai=1.0]

Read on arXiv cs.AI →

AI-generated summary · Google Gemini · from 1 sources. How we write summaries →

Chest X-ray AI models show limited real-world performance in multinational study

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The cluster is a research paper published on arXiv detailing a study on AI model performance. [lever_c_demoted from research: ic=1 ai=1.0]
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COVERAGE [1]

  1. arXiv cs.AI TIER_1 English(EN) · Qinmei Xu, Yiheng Li, Wenya Zhao, Zihao Zhao, Chuanjun Xu, Ahmet Gorkem Er, Xianghao Zhan, Brittany Dashevsky, Mohammed Alawad, Marc von der St\"uck, Marvin Gazibari\'c, Daniel Truhn, Shunsuke Shibata, Ryosuke Horino, Mio Ito, Akio Hiwatashi, Suyu Li, Me… ·

    Benchmarking Classification Tasks of Chest X-ray AI Across Multinational Public and Private Datasets: a retrospective diagnostic accuracy study

    arXiv:2505.16027v2 Announce Type: replace-cross Abstract: Chest X-ray (CXR) AI models are increasingly proposed for triage, screening, and rule-out, where the operating point is fixed to miss few abnormalities. Most evaluations instead report threshold-free discrimination on a fe…