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World's oldest tortoise, Jonathan, has genome sequenced to unlock longevity secrets

Scientists have sequenced the genome of Jonathan, a 194-year-old Aldabra giant tortoise, to understand the secrets of his extreme longevity. The study, published in Science Advances, revealed unique gene variants in Jonathan related to DNA repair, insulin regulation, and mitochondrial function. Researchers found that while most of his genome showed age-related entropy, his mitochondrial methylome appeared unusually pristine, similar to that of a much younger tortoise. This finding suggests a potential key to his exceptional lifespan, though further research is needed to fully understand the complex genetic factors involved. AI

IMPACT Unlocks potential genetic targets for human healthspan and lifespan research.

RANK_REASON Scientific paper detailing a genome sequencing of a notable animal. [lever_c_demoted from research: ic=1 ai=0.4]

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World's oldest tortoise, Jonathan, has genome sequenced to unlock longevity secrets

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Scientific paper detailing a genome sequencing of a notable animal. [lever_c_demoted from research: ic=1 ai=0.4]
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  1. 404 Media TIER_1 English(EN) · Becky Ferreira ·

    ‘Jonathan’ Is the Oldest Land Animal on Earth. He Could Hold the Secrets to Defying Death

    Jonathan, a 194-year-old Aldabra giant tortoise, was born before the Civil War. Scientists have now sequenced his genome to reveal what’s behind his extreme longevity, so we can live longer too.