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New CTTC method enhances drug repurposing accuracy

Researchers have developed a new method called Coupled Tensor-Tensor Completion (CTTC) to improve the accuracy of tensor completion problems, particularly in biomedical applications like drug repurposing. Unlike previous methods that could only incorporate matrix-based side information, CTTC can leverage tensor-based side information to uncover hidden connections among multimodal tensors. An alternating algorithm was derived to solve the CTTC optimization problem, and its convergence was established. In experiments, CTTC demonstrated superior performance and runtime compared to existing methods on benchmark datasets, showing enhanced accuracy in predicting drug effects. AI

IMPACT This method could improve the efficiency and accuracy of drug discovery and development by better predicting drug effects.

RANK_REASON The cluster contains an academic paper detailing a new computational method with applications in a scientific domain. [lever_c_demoted from research: ic=1 ai=0.7]

Read on arXiv cs.LG →

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New CTTC method enhances drug repurposing accuracy

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The cluster contains an academic paper detailing a new computational method with applications in a scientific domain. [lever_c_demoted from research: ic=1 ai=0.7]
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COVERAGE [1]

  1. arXiv cs.LG TIER_1 English(EN) · Maryam Bagherian, Albert Hung, Ivo Dinov, Joshua Welch ·

    Coupled Tensor-Tensor Completion Method with Applications in Drug Repurposing

    arXiv:2609.03190v1 Announce Type: cross Abstract: Many biomedical challenges can be posed as tensor completion problems where the observed entries of a multidimensional array (a tensor) are used to impute the missing values. In such settings, incorporating side information about …