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New SSE-Bio agent enhances multi-hop biomedical reasoning

Researchers have developed SSE-Bio, a novel agent designed for complex multi-hop reasoning in the biomedical domain. Unlike existing methods that use static retrieval or broad prompt rewriting, SSE-Bio maintains a structured state and selectively retrieves knowledge triplets and templates. This agent improves its reasoning memory through fine-grained template editing and a unique proxy-training strategy for optimizing retrieval decisions. Experiments demonstrate that SSE-Bio significantly outperforms current baselines on biomedical multi-hop QA benchmarks, achieving a notable improvement on the BioHopR dataset. AI

IMPACT This structured agent approach could improve the accuracy and reliability of AI systems in complex biomedical research and question answering.

RANK_REASON The cluster contains a research paper detailing a new model and its performance on benchmarks. [lever_c_demoted from research: ic=1 ai=1.0]

Read on arXiv cs.AI →

AI-generated summary · Google Gemini · from 1 sources. How we write summaries →

New SSE-Bio agent enhances multi-hop biomedical reasoning

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The cluster contains a research paper detailing a new model and its performance on benchmarks. [lever_c_demoted from research: ic=1 ai=1.0]
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COVERAGE [1]

  1. arXiv cs.AI TIER_1 English(EN) · Zhaohan Meng, Zaiqiao Meng, Siwei Liu, Hao Xu, Ke Yuan, Iadh Ounis ·

    SSE-Bio: A Structured Self-Evolving Agent with Agentic Retrieval Policy for Multi-Hop Biomedical Reasoning

    arXiv:2608.22132v1 Announce Type: cross Abstract: Biomedical multi-hop question answering (QA) requires models to connect evidence across intermediate entities such as diseases, drugs, proteins, and phenotypes. Existing agents typically rely on static retrieval workflows or coars…