Users are reporting that Anthropic's Opus 5 model is incorrectly flagging and falling back on bio-related requests, despite the company's documentation stating otherwise. This issue occurs even for seemingly benign scientific prompts, forcing users to switch to less capable models like Sonnet 4.6 or spend time rephrasing their queries. The problem is particularly frustrating for researchers who rely on Opus 5 for tasks such as experimental planning and data analysis, as it disrupts their workflow and contradicts Anthropic's stated policies. AI
IMPACT Potential disruption for researchers and scientists using Opus 5 for scientific tasks, highlighting ongoing challenges with AI safety guardrails.
RANK_REASON User reports of a model's unexpected behavior and contradiction with documentation.
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