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New DNA methylation clock accurately estimates zebra shark age

Researchers have developed a novel method to estimate the age of zebra sharks using DNA methylation patterns in their blood. This new epigenetic clock can predict a shark's age with a median error of one to two years, utilizing information from just a few specific spots in the genome. This breakthrough is significant because sharks, with their diverse lifespans and ancient evolutionary lineage, have been a challenge to study in terms of aging. The findings suggest that some fundamental biological mechanisms of aging, like DNA methylation patterns, may be conserved across a vast evolutionary distance, even between sharks and mammals. AI

RANK_REASON Research paper detailing a new method for aging animals using DNA methylation. [lever_c_demoted from research: ic=1 ai=0.4]

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New DNA methylation clock accurately estimates zebra shark age

COVERAGE [1]

  1. Forbes — Innovation TIER_1 English(EN) · Melissa Cristina Márquez, Contributor ·

    What Shark DNA Can Teach Us About The Biology Of Aging

    What if we could estimate a shark’s age from a small blood sample rather than counting growth rings in its vertebrae? New research on zebra sharks has developed an “epigenetic clock” that can predict age with surprising accuracy, using changes in DNA methylation at just 10 sites.…