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New framework GraphDx enhances medical diagnosis with cost-aware LLM knowledge graphs

Researchers have developed GraphDx, a novel framework designed to improve sequential diagnosis in medical settings. This system utilizes Large Language Models (LLMs) to construct Medical Diagnosis Knowledge Graphs (MDKGs) that are sensitive to both diagnostic relevance and cost. GraphDx employs three specialized agents—Perception, Reasoning, and Decision—to systematically gather information, score evidence, and plan diagnostic steps while minimizing expenses. Experiments on MedQA and MIMIC-IV datasets demonstrated significant improvements in diagnostic success rates, achieving 79-93% accuracy while simultaneously reducing testing costs by 20-54%. AI

IMPACT This framework could lead to more efficient and cost-effective medical diagnostic processes by leveraging LLMs for structured knowledge representation and reasoning.

RANK_REASON The cluster describes a new research paper detailing a novel framework for medical diagnosis. [lever_c_demoted from research: ic=1 ai=1.0]

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New framework GraphDx enhances medical diagnosis with cost-aware LLM knowledge graphs

COVERAGE [1]

  1. arXiv cs.AI TIER_1 English(EN) · Shaoting Tan, Ning Liu, Yuntao Du, Shuyue Wei, Wu Shuai, Qian Li, Yanyu Xu, Wei Zhang, Lizhen Cui, Haitao Yuan ·

    GraphDx: A Cost-Aware Knowledge-Enhanced Multi-Agent Framework for Sequential Diagnosis

    arXiv:2607.15280v1 Announce Type: new Abstract: Sequential diagnosis requires balancing diagnostic accuracy against resource costs through iterative information gathering. Existing Large Language Model (LLM) approaches exhibit a critical knowledge-reasoning gap: despite encoding …