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MedGemma-1.5-4B quantized to INT4 using llm-compressor

A technical guide details the process of quantizing Google's MedGemma-1.5-4B medical vision-language model to INT4 (W4A16) using the llm-compressor library. The author encountered and resolved several issues, including the deprecation of AutoAWQ and compatibility problems with Gemma3's architecture. The guide provides specific steps for setting up the environment, loading the model, preparing a calibration dataset, and running the quantization process, ultimately reducing the model's size from 8.6 GB to 5.2 GB for self-hosted deployment. AI

IMPACT Enables more efficient self-hosting of medical vision-language models by reducing their size.

RANK_REASON The item details a technical process for optimizing an existing model, not a new model release or research breakthrough.

Read on dev.to — LLM tag →

AI-generated summary · Google Gemini · from 1 sources. How we write summaries →

MedGemma-1.5-4B quantized to INT4 using llm-compressor

COVERAGE [1]

  1. dev.to — LLM tag TIER_1 English(EN) · JoTeq the First ·

    Quantizing MedGemma to INT4 (GPTQ/W4A16): Everything That Broke Along the Way

    <p>Quantized Google's MedGemma-1.5-4B (a medical vision-language<br /> model) to INT4 (W4A16) via <code>llm-compressor</code>'s GPTQModifier, for<br /> self-hosted deployment. 8.6 GB in BF16 -&gt; 5.2 GB quantized. Full<br /> step-by-step below, model link at the bottom.</p> <p><…