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Single cocaine exposure alters mouse brain genomes for weeks, study finds

New research presented at the Federation of European Neuroscience Societies (FENS) Forum 2026 indicates that a single exposure to cocaine can cause lasting changes in mouse brains. These alterations, observed in the genomes of dopaminergic neurons, persist for at least two weeks and may contribute to addiction by priming the brain for a stronger response to subsequent exposures. Scientists are investigating these genomic changes to better understand individual susceptibility to addiction and to potentially develop new treatments. AI

RANK_REASON Research findings on the biological impact of a substance presented at a scientific forum. [lever_c_demoted from research: ic=1 ai=0.1]

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Single cocaine exposure alters mouse brain genomes for weeks, study finds

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  1. 404 Media TIER_1 English(EN) · Becky Ferreira ·

    Scientists Gave Mice Cocaine. This Is What It Did to Their Brains

    Researchers found that a single dose left persistent changes to the genomes of neurons, a discovery that could have implications for treating addiction.