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New HDDPM model enhances low-count PET image recovery

By PulseAugur Editorial · [2 sources] ·

Researchers have developed a new method called HDDPM (Heteroscedastic Denoising Diffusion Probabilistic Model) to improve the recovery of low-count Positron Emission Tomography (PET) images. Unlike standard diffusion models that assume uniform noise, HDDPM accounts for the non-Gaussian and spatially dependent noise inherent in PET scans, particularly at low radiation doses. The model incorporates a Poisson-based variance module to generate voxel-wise noise maps, reflecting the activity-dependent noise structure. Evaluations across different scanners and dose levels showed HDDPM achieved comparable overall image quality to standard models but significantly reduced measurement errors in low-dose scenarios, demonstrating its reliability and physical motivation for quantitative PET recovery. AI

IMPACT This research could lead to more accurate medical imaging with lower radiation doses, improving diagnostic capabilities in healthcare.

RANK_REASON Research paper detailing a new model for image recovery. [lever_c_demoted from research: ic=1 ai=1.0]

Read on arXiv cs.AI →

AI-generated summary · Google Gemini · from 2 sources. How we write summaries →

New HDDPM model enhances low-count PET image recovery

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Research paper detailing a new model for image recovery. [lever_c_demoted from research: ic=1 ai=1.0]
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COVERAGE [2]

  1. arXiv cs.AI TIER_1 English(EN) · Raymond Confidence, Udunna C. Anazodo ·

    HDDPM: Heteroscedastic Denoising Diffusion Probabilistic Model for Quantitative Low-Count Brain PET Recovery

    arXiv:2606.28513v1 Announce Type: cross Abstract: Positron emission tomography (PET) seeks to balance diagnostic quality with ra-diation dose. Low-count PET noise is non-Gaussian, non-stationary, and spatial-ly dependent. It scales directly with local activity and is shaped by it…

  2. arXiv cs.CV TIER_1 English(EN) · Xuepeng Liu, Ruili Li, Zetong Liu, Renyiming Li, Yan Li, Yin Dai, Chao Li, Yueyang Teng ·

    AnF-DiffPET: Anatomy- and Frequency-Guided Diffusion for PET/CT Denoising

    arXiv:2607.00509v1 Announce Type: new Abstract: Positron emission tomography (PET) provides essential functional information for disease assessment, however reducing injected activity or acquisition time produces low-dose (LD) PET with stronger count dependent noise and less reli…

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