OmniBioTwin: A System-of-Twinned-Systems Framework for Health Digital Twins
Researchers have introduced OmniBioTwin, a novel framework designed to create more integrated and comprehensive health digital twins. This system-of-twinned-systems approach organizes digital twins as modular components that interact across different scales, from molecular to organ levels. The framework includes seven coordinated layers, facilitating data integration, autonomous modeling, and human-in-the-loop decision support, with an initial demonstration focusing on GLP-1 signaling pathways in Alzheimer's disease. AI
IMPACT This framework could enable more sophisticated patient-specific modeling and decision support in healthcare.