ProMUSE: Progressive Multi-modal Uncertainty-guided Staged Evidential Alzheimer Disease Classification
Researchers have developed ProMUSE, a novel AI system designed to improve the early diagnosis of Alzheimer's disease by adaptively incorporating multi-modal data. This system initially uses low-cost clinical assessments and quantifies diagnostic uncertainty. If the uncertainty is high, ProMUSE progressively integrates more expensive data like MRI and PET scans, using Dempster-Shafer theory to fuse information and reduce reliance on costly imaging. Experiments on benchmark datasets show ProMUSE can achieve comparable accuracy to full-modality approaches while significantly reducing the need for MRI/PET scans, offering a more cost-effective solution for widespread screening. AI
IMPACT Enables more cost-effective and widespread early diagnosis of Alzheimer's disease by reducing reliance on expensive imaging techniques.